Matthew Bott
马修·博特
MD
Thoracic Surgeon胸外科医生
👥Biography 个人简介
Matthew Bott at MSKCC focuses on early-stage lung cancer surgery and novel detection strategies. His research integrates ctDNA liquid biopsy with surgical decision-making, aiming to refine patient selection and detect occult disease after resection.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Liquid Biopsy in Surgery
Pioneered ctDNA-based approaches to monitor minimal residual disease after lung cancer resection, identifying patients at high risk for recurrence who may benefit from adjuvant therapy.
Sublobar Resection
Contributed evidence supporting segmentectomy for small peripheral stage I NSCLC, advancing the field's shift toward lung-sparing resections without compromising oncologic outcomes.
Representative Works 代表性著作
Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic non-small cell lung cancer
Annals of Oncology (2019)
Demonstrated ctDNA dynamics as a sensitive early indicator of treatment response, supporting its integration into thoracic oncology clinical workflows.
Personalized circulating tumor DNA analysis as a predictive biomarker in resected lung cancer
JCO Precision Oncology (2021)
Validated personalized ctDNA assays for post-surgical MRD detection, informing adjuvant treatment decisions in early-stage NSCLC.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Lecia V. Sequist
Massachusetts General Hospital / Harvard Medical School
Mark G. Kris
Memorial Sloan Kettering Cancer Center
Geoffrey R. Oxnard
Foundation Medicine / Harvard Medical School
Alice T. Shaw
Novartis Institutes for BioMedical Research / Massachusetts General Hospital
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