Jhanelle E. Gray
贾内尔·格雷
MD
Senior Member and Chair, Department of Thoracic Oncology高级研究员；胸部肿瘤科主任
👥Biography 个人简介
Dr. Jhanelle Gray is a leading thoracic oncologist specializing in immunotherapy and biomarkers for NSCLC. She leads Moffitt's thoracic oncology department and conducts pivotal trials on checkpoint inhibitors, TMB, and PD-L1 in lung cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Immunotherapy Biomarker Development
Led research establishing tumor mutational burden (TMB) and PD-L1 expression as predictive biomarkers for checkpoint inhibitor response in NSCLC, supporting regulatory approval of companion diagnostics.
Checkpoint Inhibitor Clinical Trials
Key investigator on atezolizumab, nivolumab, and durvalumab trials in NSCLC, generating evidence that shapes immunotherapy sequencing and combination strategies in current practice.
Health Disparities in Lung Cancer
Researches racial and socioeconomic disparities in NSCLC outcomes and immunotherapy access, advocating for diverse clinical trial enrollment to ensure equitable benefit from immunotherapy advances.
Representative Works 代表性著作
Tumor Mutational Burden as a Biomarker for Immunotherapy in Non-Small-Cell Lung Cancer
Annals of Oncology (2019)
Characterized the predictive value of TMB across checkpoint inhibitor trials, contributing to FDA approval of pembrolizumab in high-TMB solid tumors.
Atezolizumab versus Docetaxel for Patients with Previously Treated NSCLC (OAK)
Lancet (2017)
Co-investigator on OAK trial demonstrating atezolizumab overall survival benefit over docetaxel, leading to second-line FDA approval in NSCLC.
Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer (PACIFIC)
New England Journal of Medicine (2017)
Contributing investigator establishing durvalumab consolidation as standard of care after concurrent chemoradiation in unresectable stage III NSCLC.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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Massachusetts General Hospital / Harvard Medical School
Mark G. Kris
Memorial Sloan Kettering Cancer Center
Geoffrey R. Oxnard
Foundation Medicine / Harvard Medical School
Alice T. Shaw
Novartis Institutes for BioMedical Research / Massachusetts General Hospital
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