Ana Anderson
安娜·安德森
PhD
Associate Professor of Medicine医学副教授
👥Biography 个人简介
Ana Anderson is an authority on T cell regulatory molecules in cancer, particularly TIM-3 and Th17 biology. Her research has illuminated how coinhibitory receptors cooperate to drive T cell dysfunction in tumors, informing next-generation combination immunotherapies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
TIM-3 in T Cell Exhaustion
Demonstrated that TIM-3 marks terminally exhausted tumor-infiltrating T cells and cooperates with PD-1 to enforce immune suppression in cancer.
Th17 Cells in Cancer
Characterized the role of Th17 cells and their plasticity in anti-tumor immunity, revealing context-dependent pro- and anti-tumor functions.
Representative Works 代表性著作
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
Immunity (2016)
Comprehensive analysis of next-generation checkpoint receptors, guiding combination blockade strategies in clinical oncology.
T cell Ig mucin-3 (TIM-3) signaling pathway promotes Th1 cell death and dysfunctional cytokine production
Science Signaling (2010)
Defined TIM-3 signaling mechanisms suppressing effector T cell function, supporting TIM-3 as a cancer immunotherapy target.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Philip Greenberg
Fred Hutchinson Cancer Center
Dan Littman
NYU Langone Health
Alexander Rudensky
Memorial Sloan Kettering Cancer Center
Arlene Sharpe
Harvard Medical School
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