Young-Hyuck Im
林荣赫
MD, PhD
Professor; Director, Division of Hematology-Oncology教授；血液肿瘤科主任
👥Biography 个人简介
Young-Hyuck Im, MD, PhD is a Professor and Division Director at Samsung Medical Center, one of Asia's leading breast cancer clinical research centers. He is a principal investigator for major global breast cancer trials including DESTINY-Breast series, CDK4/6 inhibitor studies, and pan-Asian research on HER2-directed therapy, contributing critical data on outcomes in Asian patient populations.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
HER2-Directed Therapy in Asian Populations
Led Korean and pan-Asian sub-studies of DESTINY-Breast trials evaluating T-DXd in HER2-positive and HER2-low MBC, providing key efficacy and safety data supporting therapy use in Asian patients who may differ in tumor biology and tolerability.
CDK4/6 Inhibitors in HR+ Breast Cancer
Conducted pivotal Asian-region studies of palbociclib, ribociclib, and abemaciclib in HR+/HER2- metastatic breast cancer, generating population-specific data that informed treatment guidelines across East Asia.
Representative Works 代表性著作
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for HER2-Positive Metastatic Breast Cancer: Asia-Pacific Subgroup Analysis (DESTINY-Breast03)
ESMO Open (2023)
Asian-subgroup analysis demonstrating consistent T-DXd superiority over T-DM1 in HER2+ MBC in Korean and Asian patients, with important ILD safety characterization.
Palbociclib plus Letrozole as First-Line Therapy in East Asian Patients with ER+/HER2- Advanced Breast Cancer: PALOMA-2 Asian Subgroup Analysis
Cancer Research and Treatment (2020)
Subgroup analysis confirming palbociclib-letrozole efficacy and tolerability in East Asian HR+ MBC patients, supporting uniform international guidelines across populations.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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