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Translational Medicine / 转化医学Precision Medicine

Naiyer A. Rizvi

M.D.

🏢Columbia University Irving Medical Center🌐USA

Director, Thoracic Oncology

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Key Papers
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Key Contributions

👥Biography 个人简介

Naiyer Rizvi is a leading thoracic oncologist who has advanced precision immunotherapy approaches for lung cancer. His research established tumor mutational burden (TMB) as a predictive biomarker for checkpoint inhibitor response, fundamentally changing how patients are selected for immunotherapy. Rizvi continues to develop next-generation biomarkers and combination strategies.

Naiyer Rizvi是领先的胸腔肿瘤学家,他推进了肺癌的精准免疫治疗方法。他的研究确立了肿瘤突变负荷(TMB)作为检查点抑制剂反应的预测性生物标志物,从根本上改变了患者免疫治疗的选择方式。Rizvi继续开发下一代生物标志物和组合策略。

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🧪Research Fields 研究领域

Lung Cancer Immunotherapy肺癌免疫治疗
Tumor Mutational Burden肿瘤突变负荷
Precision Oncology精准肿瘤学

🎓Key Contributions 主要贡献

TMB as Biomarker

Established tumor mutational burden as a pan-cancer predictive biomarker for immunotherapy.

Lung Cancer Immunotherapy

Led key trials establishing checkpoint inhibitors in NSCLC.

Representative Works 代表性著作

[1]

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Science (2015)

Landmark paper establishing TMB-response correlation.

📄Data Sources 数据来源

Last updated: 2026-03-04 | All information from publicly available academic sources

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