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Translational Medicine / 转化医学Nanomedicine & Drug Delivery

Younan Xia

夏幼南

PhD

🏢Georgia Institute of Technology(佐治亚理工学院)🌐USA

Brock Family Chair; Professor, School of Chemistry and BiochemistryBrock家族讲席教授;化学与生物化学学院教授

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h-index
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Key Papers
6
Awards
3
Key Contributions

👥Biography 个人简介

Younan Xia is the Brock Family Chair Professor at Georgia Institute of Technology in the School of Chemistry and Biochemistry and the Coulter Department of Biomedical Engineering. He is one of the most highly cited chemists and materials scientists in the world, with over 85,000 total citations. Xia is a pioneer in the synthesis of noble metal nanostructures with controlled shapes and sizes — including nanocubes, nanowires, nanocages, and nanoplates. His gold and silver nanocages have unique hollow, porous structures that can be loaded with drugs and have tunable near-infrared plasmonic properties for photothermal and photoacoustic cancer imaging and therapy. He has made foundational contributions to cancer nanomedicine, developing nanoparticle platforms for drug delivery, tumor imaging, and photothermal therapy that have been extensively validated in animal cancer models.

Younan Xia 是佐治亚理工学院化学与生物化学学院及Coulter生物医学工程系的Brock家族讲席教授。他是世界上被引用次数最多的化学家和材料科学家之一,总引用次数超过85,000次。 Xia 是具有可控形状和尺寸的贵金属纳米结构合成领域的开创者,包括纳米立方体、纳米线、纳米笼和纳米片。他的金和银纳米笼具有独特的空心多孔结构,可以装载药物,并具有可调谐的近红外等离激元特性,用于光热和光声癌症成像和治疗。

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🧪Research Fields 研究领域

Noble Metal Nanostructures贵金属纳米结构
Hollow Nanocages for Drug Delivery空心纳米笼药物递送
Photothermal & Photoacoustic Nanomedicine光热与光声纳米医学
Biodegradable Nanoparticles可生物降解纳米颗粒
Cancer Theranostics癌症诊疗一体化

🎓Key Contributions 主要贡献

Gold Nanocages for Photothermal Cancer Therapy

Developed gold nanocages — hollow, porous nanostructures with tunable NIR absorption — for simultaneous drug delivery, photothermal therapy, and photoacoustic imaging of tumors. Combined diagnostics and therapy in a single nanoplatform.

Shape-Controlled Noble Metal Nanocrystal Synthesis

Pioneered synthesis of noble metal nanocrystals with precisely controlled shapes (cubes, plates, wires, cages), enabling systematic investigation of how shape affects biological behavior and therapeutic efficacy.

Biodegradable Polymer Nanoparticles

Developed PLGA and other biodegradable polymer nanoparticles with controlled size distribution for cancer drug delivery, with systematic optimization of drug loading, release kinetics, and tumor targeting.

Representative Works 代表性著作

[1]

Gold nanocages as contrast agents for spectroscopic optical coherence tomography

Nano Letters (2005)

First demonstration of gold nanocages for optical coherence tomography cancer imaging, establishing the theranostic nanocage concept.

[2]

Gold nanocages covered with smart responsive polymers for controlled release with high efficiency

Journal of the American Chemical Society (2009)

Temperature/NIR-controlled drug release from gold nanocage platforms for cancer therapy.

🏆Awards & Recognition 奖项与荣誉

🏆National Academy of Engineering Member
🏆American Academy of Arts and Sciences Fellow
🏆ACS Award in the Chemistry of Materials
🏆MRS Medal
🏆Langmuir Lecture Award
🏆RSC Materials Chemistry Award

📄Data Sources 数据来源

Last updated: 2026-04-05 | All information from publicly available academic sources

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