Yoshino Takayuki
MD, PhD
Chief of GI Oncology Division
👥Biography 个人简介
Yoshino Takayuki at National Cancer Center Hospital East is a leader in GI oncology research who led the DESTINY-CRC01 and DESTINY-CRC02 trials demonstrating trastuzumab deruxtecan activity in HER2-positive metastatic colorectal cancer. His laboratory has characterized HER2 amplification as a driver of CRC and contributed to understanding its interaction with RAS/BRAF pathway. He has been central to Asia-Pacific colorectal cancer research and has led multiple international trials in advanced CRC. His work on biomarker-selected CRC therapy has advanced precision oncology in gastrointestinal cancers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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