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Translational Medicine / 转化医学iPSC-Derived Cell Therapy

Shinya Yamanaka

MD, PhD

🏢Center for iPS Cell Research and Application, Kyoto University🌐Japan

Director and Professor

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Key Contributions

👥Biography 个人简介

Shinya Yamanaka received the Nobel Prize in Physiology or Medicine in 2012 for discovering that mature cells can be reprogrammed to become pluripotent stem cells, a breakthrough that created the entire field of iPSC-derived cell therapy. At Kyoto University's CiRA, he has established the world's first clinical-grade iPSC stock from HLA-homozygous donors to provide immunologically compatible cells for allogeneic applications. His ongoing work focuses on expanding the iPSC stock to cover major HLA haplotypes and advancing iPSC-derived products into clinical trials for cancer and other diseases.

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🧪Research Fields 研究领域

iPSC technology invention
Cellular reprogramming
iPSC clinical applications
HLA-homozygous iPSC banking
Regenerative medicine translation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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