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Translational Medicine / 转化医学Spatial Transcriptomics Technology

Xiaowei Zhuang

PhD

🏢Harvard University🌐USA

David B. Arnold Jr. Professor of Science

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Key Contributions

👥Biography 个人简介

Dr. Xiaowei Zhuang invented MERFISH (Multiplexed Error-Robust Fluorescence In Situ Hybridization), a landmark spatial transcriptomics technology capable of imaging thousands of RNA species with single-molecule and single-cell resolution in tissue. Her technology is being applied to dissect the spatial organization of tumor-immune niches, map transcription factor activity landscapes, and resolve subcellular RNA localization patterns in cancer tissues.

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🧪Research Fields 研究领域

MERFISH spatial transcriptomics
multiplexed error-robust FISH
spatial transcriptome single-cell resolution
subcellular RNA localization
spatial mapping brain cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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