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Translational Medicine / 转化医学BTK Resistance Mechanisms
Jennifer Woyach
MD
🏢The Ohio State University Comprehensive Cancer Center🌐USA
Professor of Internal Medicine, Hematology
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Key Papers
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Key Contributions
👥Biography 个人简介
Jennifer Woyach characterized BTK C481S and related mutations as key mechanisms of resistance to covalent BTK inhibitors. Her work directly informed the development of non covalent inhibitors such as pirtobrutinib. She leads clinical trials in CLL and mantle cell lymphoma.
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🧪Research Fields 研究领域
CLL
BTK inhibitors
resistance mechanisms
BTK C481S
clinical translation
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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