William F. Young Jr.
小威廉·F·杨
MD, MSc
Professor of Medicine and Consultant in Endocrinology医学教授兼内分泌科顾问医师
👥Biography 个人简介
William F. Young Jr. at Mayo Clinic is the foremost global authority on primary aldosteronism and adrenal Conn syndrome, having defined modern diagnostic criteria, subtype classification, and treatment algorithms. His research transformed primary aldosteronism from a clinical rarity to the most common curable form of hypertension.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Primary Aldosteronism Diagnostic Framework
Established the aldosterone-to-renin ratio as the preferred screening test and defined confirmatory testing protocols for primary aldosteronism adopted worldwide.
Adrenal Vein Sampling Standardization
Defined technical standards and interpretation criteria for adrenal vein sampling, the gold-standard procedure for lateralizing aldosterone excess before surgery.
Unilateral vs. Bilateral Disease Management
Led studies distinguishing aldosterone-producing adenoma from bilateral adrenal hyperplasia, enabling targeted adrenalectomy with high cure rates for unilateral disease.
Representative Works 代表性著作
Primary Aldosteronism: Executive Summary from the American Endocrine Society Clinical Practice Guideline
Journal of Clinical Endocrinology & Metabolism (2016)
Authoritative guideline covering case detection, confirmatory testing, subtype differentiation, and treatment for primary aldosteronism.
Diagnosis and Treatment of Primary Aldosteronism: Practical Clinical Perspectives
Journal of Internal Medicine (2019)
Comprehensive clinical review updating diagnostic algorithms and treatment outcomes based on large Mayo Clinic cohort data.
Pheochromocytoma and Paraganglioma
New England Journal of Medicine (2019)
Widely cited NEJM review article establishing current diagnostic and management standards for catecholamine-secreting tumors.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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