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Translational Medicine / 转化医学Chronic Lymphocytic Leukemia, Venetoclax

William G. Wierda

MD, PhD

🏢University of Texas MD Anderson Cancer Center🌐USA

Professor and Medical Director, Leukemia; Chief, CLL Section

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👥Biography 个人简介

William Wierda is a world-leading CLL clinician-investigator who has contributed to development of virtually every major CLL therapy over the past two decades. He led pivotal studies establishing venetoclax-based fixed-duration regimens in both treatment-naive and relapsed/refractory CLL, including the landmark CLL14 trial of venetoclax plus obinutuzumab. His research program investigates MRD-guided treatment duration and sequencing of targeted agents. He has trained numerous CLL investigators and leads NCI-sponsored cooperative group CLL studies.

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🧪Research Fields 研究领域

venetoclax CLL
venetoclax plus obinutuzumab
CLL14 trial
fixed-duration venetoclax
MRD-guided CLL therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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