William R. Sellers
M.D.
Director, Cancer Program
👥Biography 个人简介
William Sellers leads the Cancer Program at the Broad Institute, driving large-scale functional genomics efforts to identify cancer vulnerabilities. His research has characterized synthetic lethal interactions and developed CRISPR-based screening platforms for therapeutic target discovery. Previously, he led oncology research at Novartis.
William Sellers领导布罗德研究所的癌症项目,推动大规模功能基因组学工作以识别癌症脆弱性。他的研究描述了合成致死相互作用,并开发了用于治疗靶点发现的基于CRISPR的筛选平台。此前,他曾在诺华领导肿瘤学研究。
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Cancer Dependency Map
Leading DepMap project systematically identifying cancer vulnerabilities.
PTEN Biology
Characterized PTEN tumor suppressor function and therapeutic implications.
Representative Works 代表性著作
Defining a Cancer Dependency Map
Cell (2017)
Cancer Dependency Map methodology paper.
📄Data Sources 数据来源
Last updated: 2026-03-05 | All information from publicly available academic sources
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