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Translational Medicine / 转化医学Cancer Functional Genomics, Cancer Dependencies

William Hahn

MD PhD

🏢Dana-Farber Cancer Institute🌐USA

Chief Scientific Officer

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Key Contributions

👥Biography 个人简介

William Hahn at Dana-Farber has led major functional genomics efforts to map cancer cell dependencies systematically. His leadership of the Cancer Dependency Map (DepMap) project — using CRISPR and RNAi screens across hundreds of cancer cell lines to identify genetic vulnerabilities — has created an invaluable resource for identifying cancer-specific therapeutic targets. His work connecting oncogene expression to specific cellular vulnerabilities has guided multiple drug discovery programs.

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🧪Research Fields 研究领域

cancer dependency maps
cancer cell line profiling
CRISPR screens cancer
Achilles project
oncogene function

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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