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Translational Medicine / 转化医学Cancer Pharmacogenomics, Drug Metabolism

William Bhatt

PhD

🏢St. Jude Children's Research Hospital🌐USA

Professor of Cancer Pharmacology

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Key Contributions

👥Biography 个人简介

William Bhatt is a leading researcher in cancer pharmacogenomics who investigates how genetic variation in drug metabolizing enzymes affects chemotherapy efficacy and toxicity. His research has characterized the impact of CYP450 polymorphisms on the pharmacokinetics of key oncology agents including irinotecan, tamoxifen, and fluoropyrimidines. He has developed pharmacogenomic dosing algorithms to individualize chemotherapy based on patient genotype. His work bridges pharmacology and genomics to improve cancer treatment safety and outcomes.

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🧪Research Fields 研究领域

pharmacogenomics
drug metabolism
chemotherapy dosing
CYP450 enzymes
cancer pharmacology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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