Weidong Han
韩卫东
MD, PhD
Director, Department of Biotherapy; Director, Molecular & Immunological Oncology Laboratory生物治疗科主任；分子与免疫肿瘤学实验室主任
👥Biography 个人简介
Weidong Han is a pioneer of CAR-T cell therapy in China, leading one of the first Chinese CAR-T programs for hematologic malignancies at the PLA General Hospital. His team developed and clinically tested CD19 and BCMA CAR-T constructs, establishing China as a major center of CAR-T innovation.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CAR-T Pioneering in China
Established one of China's first clinical CAR-T programs, treating ALL and lymphoma patients with CD19-targeted CAR-T cells and reporting early results that validated the approach in Chinese patient populations.
BCMA CAR-T for Multiple Myeloma
Led early BCMA-targeted CAR-T clinical trials in China, contributing to global understanding of CAR-T efficacy and safety in relapsed/refractory multiple myeloma.
Representative Works 代表性著作
CD19-targeted chimeric antigen receptor T-cell therapy for CNS relapsed or refractory acute lymphocytic leukaemia: a single-arm, phase 1/2 study
Lancet Haematology (2021)
Reported efficacy and safety of CD19 CAR-T in CNS-relapsed ALL, a difficult subset, demonstrating CNS penetration and clinical benefit.
Chimeric antigen receptor-modified T cells for solid tumors: challenges and prospects
Journal of Immunology Research (2015)
Early influential Chinese review outlining barriers of CAR-T in solid tumors and proposing strategies that guided subsequent research directions.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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