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Translational Medicine / 转化医学CDK12 Synthetic Lethality
Wayne Miles
PhD
🏢Ohio State University🌐USA
Associate Professor
30
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Key Papers
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Key Contributions
👥Biography 个人简介
Wayne Miles studies the regulation of RNA processing and translation in cancer with a focus on CDK12 and related kinases that control transcription elongation. His laboratory identifies synthetic lethal interactions that can be exploited therapeutically in CDK12 altered tumors. He uses CRISPR screens and proteomics to map new drug targets.
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🧪Research Fields 研究领域
CDK12
RNA processing
translation
synthetic lethality
functional genomics
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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