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Translational Medicine / 转化医学Quantum Dots, Nanoparticle EPR Effect

Warren Chan

MD

🏢University of Toronto🌐Canada

Professor of Biomedical Engineering

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Key Contributions

👥Biography 个人简介

Warren Chan at the University of Toronto is a pioneer of quantum dot technology for cancer imaging and has made fundamental contributions to understanding nanoparticle-tumor interactions. His landmark paper critically re-examining the EPR effect has re-shaped the field by demonstrating that nanoparticle accumulation in tumors occurs primarily through active cellular uptake rather than passive EPR. This has redirected nanomedicine development toward active targeting strategies.

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🧪Research Fields 研究领域

quantum dots imaging
nanoparticle tumor delivery
EPR effect revisited
intravital imaging nanoparticles
gold nanoparticle cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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