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Translational Medicine / 转化医学TGF-beta, Treg Differentiation, Tumor Immunosuppression

Wanjun Chen

MD

🏢National Cancer Institute🌐USA

Senior Investigator

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Key Papers
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Key Contributions

👥Biography 个人简介

Wanjun Chen at NCI has made contributions to understanding TGF-beta's role in regulatory T cell differentiation and immune suppression in the tumor microenvironment. His work on how TGF-beta converts naive T cells into Foxp3+ regulatory T cells, the relevance of this process in the tumor microenvironment, and the therapeutic implications of TGF-beta inhibition for cancer immunotherapy has been important for understanding immunosuppressive mechanisms.

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🧪Research Fields 研究领域

TGF-beta Treg differentiation
TGF-beta tumor immunosuppression
Foxp3 TGF-beta
TGF-beta cancer immune evasion
induced Treg cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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