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Translational Medicine / 转化医学MMR Discovery, Colorectal Cancer Genetics
Bert Vogelstein
MD
🏢Johns Hopkins University🌐USA
Director, Ludwig Center
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Key Contributions
👥Biography 个人简介
Bert Vogelstein is a pioneer of colorectal cancer genetics whose laboratory co-identified mismatch repair gene defects underlying hereditary nonpolyposis colorectal cancer (Lynch syndrome). His landmark MMR discoveries established the molecular basis of MSI-H cancers.
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🧪Research Fields 研究领域
mismatch repair discovery
Lynch syndrome genes
APC CRC
tumor suppressor
MSI-H colorectal
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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