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Translational Medicine / 转化医学Milestone 800 Oncology Figures

Bert Vogelstein

MD

🏢Johns Hopkins University🌐USA

Clayton Professor of Oncology, Director of Ludwig Center

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Key Contributions

👥Biography 个人简介

Bert Vogelstein is the most cited cancer researcher in history who defined the multi-step genetic model of colorectal cancer progression. His discovery of p53 mutations as the most common genetic alteration in cancer transformed understanding of tumor suppression. He pioneered ctDNA-based liquid biopsy technology with CancerSEEK for multi-cancer early detection.

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🧪Research Fields 研究领域

Cancer genomics
Tumor suppressor genes
Colorectal cancer genetics
Liquid biopsy
Cancer evolution

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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