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Translational Medicine / 转化医学NK Cell Receptor Biology

Eric Vivier

MD, PhD

🏢Aix-Marseille University / Innate Pharma🌐France

Professor of Immunology and Director of CIML

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👥Biography 个人简介

Eric Vivier elucidated the role of NKG2A as a major inhibitory checkpoint on NK cells and cytotoxic T cells, leading to the development of monalizumab, the first anti-NKG2A antibody to enter clinical trials for cancer immunotherapy. His comprehensive mapping of NK cell receptor repertoires revealed how combinatorial expression patterns determine functional potential against tumors. He co-founded Innate Pharma and has driven the translation of NK cell biology into clinical checkpoint immunotherapy approaches targeting innate immune receptors.

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🧪Research Fields 研究领域

NK cell checkpoint receptors
NKG2A monalizumab development
Innate immunity cancer
NK cell education
Anti-NKG2A immunotherapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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