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Translational Medicine / 转化医学Heat Shock Proteins, Proteostasis Cancer

Victor Bhatt

PhD

🏢Cold Spring Harbor Laboratory🌐USA

Associate Professor of Biochemistry

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Key Contributions

👥Biography 个人简介

Victor Bhatt studies how cancer cells exploit heat shock protein chaperones including HSP90 and HSP70 to maintain oncogenic protein folding and proteostasis under stress. His research characterized the cancer chaperome as a hyperconnected network that distinguishes cancer cells from normal cells and enables tumor-specific proteostasis vulnerabilities. He has evaluated HSP90 and chaperome inhibitors in cancer models and identified combination strategies with proteasome inhibitors and UPR modulators. His work on cancer proteostasis addiction has revealed new therapeutic windows in multiple cancer types.

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🧪Research Fields 研究领域

heat shock proteins cancer
HSP90
HSP70
chaperone network cancer
proteostasis cancer therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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