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Translational Medicine / 转化医学Anti-LAG3 Relatlimab, IO Combination Lung Cancer

Vamsidhar Velcheti

MD

🏢New York University Langone Health / Perlmutter Cancer Center🌐USA

Professor and Chief, Hematology and Medical Oncology

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👥Biography 个人简介

Vamsidhar Velcheti is a thoracic oncologist who has contributed to clinical investigation of anti-LAG3 checkpoint inhibitor combinations, including studies of relatlimab plus nivolumab in thoracic malignancies following the FDA approval of the combination in melanoma based on RELATIVITY-047. He has contributed to biomarker analyses identifying LAG3 expression thresholds and immune gene signatures that correlate with dual checkpoint inhibitor response. He leads multiple IO combination trials in NSCLC and has been an advocate for next-generation checkpoint inhibitor development.

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🧪Research Fields 研究领域

anti-LAG3 relatlimab RELATIVITY-047
LAG3 checkpoint inhibitor biology
nivolumab relatlimab melanoma
IO combinations NSCLC lung cancer
biomarkers dual checkpoint inhibitor response

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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