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Translational Medicine / 转化医学Cancer Neoantigens, Immunotherapy Prediction

Valsamo Anagnostou

MD PhD

🏢Johns Hopkins Sidney Kimmel Cancer Center🌐USA

Associate Professor

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Key Contributions

👥Biography 个人简介

Valsamo Anagnostou at Hopkins has made contributions to understanding how tumor neoantigens and clonal evolution influence immunotherapy response and resistance. Her research on how clonal neoantigens (present in all tumor cells) versus subclonal neoantigens predict immunotherapy response, and on how immune editing drives loss of immunogenic neoantigens during tumor evolution, has revealed fundamental connections between cancer evolution and immune evasion.

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🧪Research Fields 研究领域

neoantigen prediction
TMB immunotherapy
cancer neoepitome
tumor clonal neoantigens
immunotherapy resistance clonal evolution

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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