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hematopoietic-transplant / hematopoietic-transplantHaploidentical Transplantation

Usama Gergis

乌萨马·格尔吉斯

MD, MBA

🏢Thomas Jefferson University / Sidney Kimmel Cancer Center(托马斯·杰斐逊大学/西德尼·金梅尔癌症中心)🌐USA

Professor of Medicine; Director, Hematopoietic Stem Cell Transplantation and Cellular Therapy Program医学教授,造血干细胞移植与细胞治疗项目主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Usama Gergis is a distinguished transplant physician who has led innovative programs in haploidentical stem cell transplantation and cellular therapy. Formerly at Weill Cornell Medicine, he pioneered post-transplant cyclophosphamide-based haploidentical platforms that dramatically expand donor availability, particularly for patients lacking matched donors.

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🧪Research Fields 研究领域

Haploidentical Transplant单倍体移植
Post-Transplant Cyclophosphamide移植后环磷酰胺
HSCT造血干细胞移植
Cellular Therapy细胞治疗

🎓Key Contributions 主要贡献

Haploidentical Transplantation

Established and optimized haploidentical HSCT programs using post-transplant cyclophosphamide, enabling transplantation for patients without matched siblings or unrelated donors.

Alternative Donor Platform Development

Developed institutional protocols integrating bone marrow and peripheral blood stem cell grafts in haploidentical settings, comparing GvHD rates and immune reconstitution across platforms.

Cellular Therapy Program Leadership

Built comprehensive cellular therapy programs incorporating CAR-T cell therapy alongside transplant, managing complex referrals including relapsed/refractory lymphoma and leukemia.

Representative Works 代表性著作

[1]

Haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide for hematologic malignancies

Biology of Blood and Marrow Transplantation (2016)

Reported single-institution outcomes of PTCy-based haplo transplant, demonstrating low rates of severe GvHD and encouraging survival.

[2]

Reduced-intensity conditioning haploidentical transplantation with post-transplant cyclophosphamide: an update

Blood Advances (2020)

Updated analysis showing durable responses with RIC haplo-PTCy across diverse hematologic malignancies in older patients.

[3]

Allogeneic stem cell transplantation for older patients with acute myeloid leukemia

Current Oncology Reports (2018)

Reviewed evidence and practical approach to transplantation in elderly AML, addressing reduced-intensity and haploidentical strategies.

🏆Awards & Recognition 奖项与荣誉

🏆American Society for Transplantation and Cellular Therapy Symposium Faculty Award
🏆Sidney Kimmel Cancer Center Innovator Award
🏆Weill Cornell Medicine Excellence in Clinical Research Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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