Sergio Giralt
塞尔吉奥·吉拉尔特
MD
Chief, Adult Bone Marrow Transplant Service; Melvin Berlin Family Chair成人骨髓移植科主任,梅尔文·柏林家族讲席教授
👥Biography 个人简介
Sergio Giralt is a globally recognized leader in autologous stem cell transplantation for hematologic malignancies, particularly multiple myeloma. At MSKCC he has led major clinical trials establishing transplant consolidation as a standard of care and innovated conditioning regimens to improve response depth and tolerability.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Autologous Transplant in Myeloma
Led pivotal trials integrating novel agents with high-dose melphalan conditioning, demonstrating superior complete response rates and progression-free survival in multiple myeloma.
Tandem Transplantation
Contributed to defining the role of tandem autologous transplantation for high-risk myeloma, including landmark comparisons with single transplant strategies.
Reduced-Intensity Conditioning
Advanced reduced-intensity conditioning platforms enabling transplantation in older and comorbid patients with hematologic malignancies previously considered ineligible.
Representative Works 代表性著作
Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies
Blood (2001)
Established reduced-intensity conditioning as a feasible transplant approach for older or medically unfit patients.
Salvage autologous stem cell transplantation with high-dose carmustine, etoposide, cytarabine, and melphalan for multiple myeloma
Biology of Blood and Marrow Transplantation (2012)
Defined salvage transplant outcomes in relapsed myeloma, informing sequencing of therapy.
Consolidation therapy with autologous SCT in multiple myeloma: a systematic review
Bone Marrow Transplantation (2018)
Comprehensive review cementing the role of upfront autologous transplant in myeloma management.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Effie Petersdorf
Fred Hutchinson Cancer Center
Miguel-Angel Perales
Memorial Sloan Kettering Cancer Center
Joseph H. Antin
Dana-Farber Cancer Institute / Brigham and Women's Hospital
Stephanie J. Lee
Fred Hutchinson Cancer Center
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