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hematopoietic-transplant / hematopoietic-transplantAutologous Stem Cell Transplantation

Sergio Giralt

塞尔吉奥·吉拉尔特

MD

🏢Memorial Sloan Kettering Cancer Center(纪念斯隆-凯特琳癌症中心)🌐USA

Chief, Adult Bone Marrow Transplant Service; Melvin Berlin Family Chair成人骨髓移植科主任,梅尔文·柏林家族讲席教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Sergio Giralt is a globally recognized leader in autologous stem cell transplantation for hematologic malignancies, particularly multiple myeloma. At MSKCC he has led major clinical trials establishing transplant consolidation as a standard of care and innovated conditioning regimens to improve response depth and tolerability.

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🧪Research Fields 研究领域

Autologous Transplant自体移植
Multiple Myeloma多发性骨髓瘤
HSCT造血干细胞移植
Conditioning Regimens预处理方案

🎓Key Contributions 主要贡献

Autologous Transplant in Myeloma

Led pivotal trials integrating novel agents with high-dose melphalan conditioning, demonstrating superior complete response rates and progression-free survival in multiple myeloma.

Tandem Transplantation

Contributed to defining the role of tandem autologous transplantation for high-risk myeloma, including landmark comparisons with single transplant strategies.

Reduced-Intensity Conditioning

Advanced reduced-intensity conditioning platforms enabling transplantation in older and comorbid patients with hematologic malignancies previously considered ineligible.

Representative Works 代表性著作

[1]

Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies

Blood (2001)

Established reduced-intensity conditioning as a feasible transplant approach for older or medically unfit patients.

[2]

Salvage autologous stem cell transplantation with high-dose carmustine, etoposide, cytarabine, and melphalan for multiple myeloma

Biology of Blood and Marrow Transplantation (2012)

Defined salvage transplant outcomes in relapsed myeloma, informing sequencing of therapy.

[3]

Consolidation therapy with autologous SCT in multiple myeloma: a systematic review

Bone Marrow Transplantation (2018)

Comprehensive review cementing the role of upfront autologous transplant in myeloma management.

🏆Awards & Recognition 奖项与荣誉

🏆Robert A. Kyle Award, International Myeloma Society
🏆Distinguished Service Award, American Society for Transplantation and Cellular Therapy
🏆Top Doctor, New York Magazine

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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