Stephanie J. Lee
斯蒂芬妮·李
MD, MPH
Associate Director, Clinical Research Division; Professor, University of Washington临床研究部副主任，华盛顿大学教授
👥Biography 个人简介
Stephanie Lee is the world's foremost expert on chronic graft-versus-host disease (cGvHD) and patient-reported outcomes after hematopoietic cell transplantation. She leads the NIH Chronic GvHD Consortium and has transformed cGvHD assessment and treatment through validated measurement tools and landmark multicenter clinical trials.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Chronic GvHD Measurement and Classification
Co-led development of the NIH Consensus Criteria for cGvHD diagnosis and staging, now the global standard for clinical trials and clinical practice worldwide.
Patient-Reported Outcomes in Transplant
Developed and validated the Lee Symptom Scale and other PRO instruments capturing the patient experience of cGvHD and transplant recovery.
cGvHD Treatment Trials
Led pivotal multicenter trials of novel cGvHD therapies including ibrutinib and belumosudil, contributing to FDA approvals that changed standard of care.
Representative Works 代表性著作
NIH Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease
Biology of Blood and Marrow Transplantation (2005)
Landmark consensus establishing standardized cGvHD diagnostic and response criteria used globally in research and practice.
Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
Blood (2017)
Phase 1b/2 trial supporting FDA approval of ibrutinib as the first targeted agent for cGvHD.
Development and validation of a scale to measure symptoms of chronic graft-versus-host disease
Biology of Blood and Marrow Transplantation (2002)
Introduced the Lee Symptom Scale, widely used in cGvHD trials as a primary patient-reported endpoint.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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