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Translational Medicine / 转化医学mRNA Cancer Vaccines, Personalized Immunotherapy

Ugur Sahin

MD

🏢BioNTech SE🌐Germany

Co-Founder and CEO

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Key Contributions

👥Biography 个人简介

Ugur Sahin co-founded BioNTech and has been the driving force behind mRNA cancer vaccine development, including personalized neoantigen-based mRNA vaccines. His laboratory pioneered the BNT111 (melanoma TAA vaccine) and BNT113 (HPV-positive head and neck cancer) programs that have shown clinical activity in combination with pembrolizumab. He developed the framework for individualized mRNA vaccines manufactured from patient tumor sequencing data within weeks. His work represents the convergence of cancer genomics, immune oncology, and mRNA medicine.

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🧪Research Fields 研究领域

mRNA cancer vaccines
personalized neoantigen vaccines
BNT111
BNT113
mRNA lipid nanoparticles

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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