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Translational Medicine / 转化医学tRNA Modification, Cancer Translation

Tsutomu Suzuki

PhD

🏢University of Tokyo🌐Japan

Professor, Department of Chemistry and Biotechnology

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Key Contributions

👥Biography 个人简介

Tsutomu Suzuki is a world authority on tRNA modifications, having identified numerous novel modifications and their biosynthetic enzymes. His work revealed that cancer cells exploit tRNA modification reprogramming to enhance translation of oncogenic mRNAs with biased codon usage. He has uncovered how mitochondrial tRNA modification defects contribute to metabolic reprogramming in cancer.

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🧪Research Fields 研究领域

tRNA modifications cancer
wobble base modification
mitochondrial tRNA
translation fidelity
codon-biased translation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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