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Translational Medicine / 转化医学Milestone IO Approvals

Suzanne Topalian

MD

🏢Johns Hopkins Sidney Kimmel Comprehensive Cancer Center🌐USA

Professor of Surgery and Oncology, Associate Director Bloomberg-Kimmel Institute

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👥Biography 个人简介

Suzanne Topalian led the first-in-human studies of anti-PD-1 nivolumab showing durable responses across multiple solid tumors, directly leading to first PD-1 approvals. She shared the 2024 Lasker-DeBakey Clinical Medical Research Award for PD-1 immunotherapy development. She directs translational IO at Johns Hopkins.

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🧪Research Fields 研究领域

PD-1 blockade clinical
anti-PD-1 first trials
Lasker Award
immunotherapy translational
neoadjuvant IO

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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