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Translational Medicine / 转化医学Genitourinary Oncology, RCC Frontline Systemic Therapy

Toni Choueiri

MD

🏢Dana-Farber Cancer Institute🌐USA

Director, Lank Center for Genitourinary Oncology

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Key Contributions

👥Biography 个人简介

Toni Choueiri is widely regarded as the most influential clinical researcher in advanced renal cell carcinoma globally. He has led or co-led most of the landmark RCC trials that changed the standard of care over the past two decades, including CheckMate-9ER and the CLEAR trial. His research on belzutifan and HIF-2alpha pathway inhibition in VHL disease and RCC opened a new class of targeted agents. He leads the IMDC prognostic tool widely used in RCC.

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🧪Research Fields 研究领域

RCC frontline IO TKI combinations
nivolumab cabozantinib CheckMate-9ER
lenvatinib pembrolizumab CLEAR trial
belzutifan HIF-2alpha
RCC translational research

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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