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Translational Medicine / 转化医学Neoantigen/T Cell Recognition, MHC Restriction

Ton Schumacher

PhD

🏢Netherlands Cancer Institute🌐Netherlands

Professor and Group Leader

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Key Contributions

👥Biography 个人简介

Ton Schumacher has developed transformative technologies for studying neoantigen-specific T cell responses in cancer patients. His DNA barcode-labeled MHC multimer platform enables high-throughput identification of tumor-reactive T cells. He has revealed how MHC genotype shapes the neoantigen landscape and influences immunotherapy response, establishing fundamental principles of T cell recognition in cancer immunology.

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🧪Research Fields 研究领域

neoantigen T cell recognition
MHC restriction
T cell receptor repertoire
tumor-reactive TIL
barcode-labeled MHC multimers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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