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Translational Medicine / 转化医学HSV Oncolytic Virus, G47delta Glioma

Tomoki Todo

MD PhD

🏢University of Tokyo🌐Japan

Professor

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Key Contributions

👥Biography 个人简介

Tomoki Todo at Tokyo developed G47delta — a triple-mutated oncolytic herpes simplex virus engineered for enhanced tumor selectivity and safety — which received conditional approval in Japan for recurrent glioblastoma in 2021, the first oncolytic virus approval for brain cancer. His development of progressively refined engineered HSV-1 oncolytic vectors and their clinical translation represents an important contribution to oncolytic virotherapy.

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🧪Research Fields 研究领域

G47delta oncolytic HSV glioma
triple-mutant herpes oncolytic
oncolytic virus Japan
glioblastoma oncolytic therapy
HSV-1 engineered oncolytic

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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