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Translational Medicine / 转化医学Neoadjuvant NSCLC Biomarkers

Tina Cascone

MD, PhD

🏢MD Anderson Cancer Center🌐USA

Associate Professor of Thoracic-Head and Neck Medical Oncology

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👥Biography 个人简介

Tina Cascone led the NEOSTAR platform trial investigating neoadjuvant nivolumab with and without ipilimumab and chemotherapy in resectable NSCLC, defining major pathologic response as a surrogate endpoint. Her translational work links pathologic response to tumor microenvironment remodeling and immune signatures. She advances biomarker-driven neoadjuvant selection.

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🧪Research Fields 研究领域

NEOSTAR trial
neoadjuvant nivolumab plus ipilimumab
major pathologic response
tumor microenvironment remodeling
NSCLC biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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