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Translational Medicine / 转化医学Therapy-Related MDS, Clonal Evolution

Timothy Graubert

MD

🏢Massachusetts General Hospital🌐USA

Chief, Leukemia Center

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Key Contributions

👥Biography 个人简介

Timothy Graubert investigates therapy-related MDS and AML, characterizing the clonal evolution from CHIP through frank malignancy following cytotoxic therapy. His laboratory has defined splicing factor mutations as drivers of MDS pathogenesis.

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🧪Research Fields 研究领域

therapy-related MDS
clonal evolution leukemia
splicing factor mutations
SF3B1 mutations
genomic MDS

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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