Theodore DeWeese
西奥多·德维斯
MD
Professor and Chair of Radiation Oncology and Molecular Radiation Sciences放射肿瘤学与分子放射科学教授兼主任
👥Biography 个人简介
Theodore DeWeese is Chair of Radiation Oncology at Johns Hopkins, where he integrates radiation biology research with clinical expertise in prostate and head-and-neck cancers. His work spans translational research connecting molecular mechanisms of radiation response to improved clinical protocols.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Prostate Cancer Gene Therapy and Radiation
Developed innovative combined approaches using gene-directed enzyme prodrug therapy with radiation for prostate cancer, advancing translational research from bench to early-phase clinical trials.
Radiation Biology and DNA Repair
Investigated molecular pathways of radiation-induced DNA damage and repair, informing strategies to sensitize tumors while protecting normal tissues during radiotherapy.
Representative Works 代表性著作
A phase I study of an adenovirus-based gene therapy for prostate cancer
Clinical Cancer Research (2001)
Demonstrated feasibility and safety of combining gene therapy with radiation in prostate cancer, opening translational avenues for combined modality treatment.
Radiation sensitivity of prostate cancer cell lines: a comparison of dose-response parameters
International Journal of Radiation Oncology Biology Physics (1998)
Established radiobiological parameters foundational to clinical dose prescription in prostate cancer radiotherapy.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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