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radiation-oncology / radiation-oncologyHead and Neck Cancer Radiation

Paul M. Harari

保罗·哈拉里

MD

🏢University of Wisconsin School of Medicine and Public Health(威斯康星大学医学与公共卫生学院)🌐USA

Chairman and Doris Albright Mower Professor, Department of Human Oncology人类肿瘤学系主任兼多丽丝·阿尔布莱特·莫尔教授

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Paul Harari is a national leader in head and neck cancer radiation oncology at University of Wisconsin. He pioneered molecularly targeted radiosensitization strategies, particularly EGFR inhibition combined with radiotherapy, shaping standard-of-care protocols for locally advanced HNSCC.

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🧪Research Fields 研究领域

Radiation Oncology放射肿瘤学
Head and Neck Cancer头颈部癌症
EGFR-Targeted TherapyEGFR靶向治疗
Chemoradiation放化疗

🎓Key Contributions 主要贡献

Cetuximab + Radiotherapy Standard of Care

Pioneered clinical use of cetuximab combined with radiotherapy for locally advanced head and neck cancer, establishing a new treatment standard.

EGFR Radiosensitization Strategy

Led translational studies defining EGFR pathway modulation as a radiosensitization strategy in squamous cell carcinomas.

NRG/RTOG Cooperative Group Trials

Directed multi-institutional cooperative group trials improving locoregional control rates in head and neck malignancies.

Representative Works 代表性著作

[1]

Molecular target modulation, imaging, and dosimetry studies in cetuximab-treated head and neck cancer patients

Clinical Cancer Research (2010)

Linked cetuximab tumor uptake to EGFR inhibition and radiosensitization in vivo.

[2]

Bioradiotherapy: the added value of radiotherapy to molecularly targeted treatments

Seminars in Radiation Oncology (2006)

Defined the conceptual framework for molecularly targeted radiosensitization strategies.

🏆Awards & Recognition 奖项与荣誉

🏆ASTRO Fellow
🏆American Head and Neck Society Distinguished Achievement Award
🏆UW Distinguished Faculty Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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