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Translational Medicine / 转化医学Single-Cell Cancer Atlas

Sarah Teichmann

PhD

🏢Wellcome Sanger Institute🌐UK

Head of Cellular Genetics

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Key Contributions

👥Biography 个人简介

Sarah Teichmann co-leads the Human Cell Atlas and has built comprehensive single-cell atlases of immune cells in cancer, revealing the diversity and functional states of tumor-infiltrating lymphocytes across cancer types. Her work on T cell receptor repertoire analysis from single-cell data has enabled tracking of clonal T cell dynamics during immunotherapy response and resistance. Her development of computational tools for cell-cell interaction inference from single-cell transcriptomics has become standard in tumor microenvironment analysis.

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🧪Research Fields 研究领域

Human Cell Atlas coordination
Immune cell atlas
T cell receptor repertoire analysis
Single-cell multi-omics
Tumor-immune cell interaction mapping

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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