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Translational Medicine / 转化医学SCLC Clinical Trials, Novel Therapeutics

Taofeek Owonikoko

MD, PhD

🏢UPMC Hillman Cancer Center / University of Pittsburgh🌐USA

Professor and Vice Chair for Research, Hematology-Oncology

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Key Contributions

👥Biography 个人简介

Taofeek Owonikoko is a thoracic oncologist and SCLC clinical trials expert who has led or participated in pivotal studies of novel agents including lurbinectedin, trilaciclib, and DLL3-directed bispecific antibodies such as AMG 757 (tarlatamab). His research has contributed to the FDA approvals of lurbinectedin for platinum-refractory SCLC and trilaciclib as myeloprotection during chemotherapy. He investigates biological predictors of treatment response in SCLC and has led NCI-CTEP trials. His contributions span drug development, resistance mechanisms, and translational biomarker research in SCLC.

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🧪Research Fields 研究领域

SCLC lurbinectedin
trilaciclib CDK4/6 myeloprotection SCLC
AMG 757 DLL3 bispecific SCLC
SCLC relapsed refractory treatment
SCLC BET bromodomain inhibitors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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