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Translational Medicine / 转化医学Colorectal Cancer, KRAS Targeting

Tanios Bekaii-Saab

MD

🏢Mayo Clinic🌐USA

Vice Chair and Section Chief of GI Oncology

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👥Biography 个人简介

Tanios Bekaii-Saab at Mayo Clinic is a leader in gastrointestinal oncology with particular expertise in KRAS-targeted approaches in colorectal cancer. He has been involved in the development and clinical evaluation of KRAS G12C inhibitors in CRC and has led multiple phase I/II trials testing novel KRAS-targeting strategies. His research group has been active in defining optimal combination strategies that overcome feedback resistance to KRAS G12C inhibition. He has also contributed to understanding KRAS G12D inhibitors and next-generation approaches to target KRAS-mutant CRC.

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🧪Research Fields 研究领域

KRAS G12C sotorasib CRC
KRAS G12D CRC therapy
CodeBreaK CRC trial
GI oncology targeted therapy
CRC clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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