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Translational Medicine / 转化医学Cytokines in Cancer, Melanoma Immunotherapy
Mario Sznol
MD
🏢Yale School of Medicine🌐USA
Professor of Medicine (Medical Oncology)
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Key Papers
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Key Contributions
👥Biography 个人简介
Mario Sznol led high-dose IL-2 therapy for melanoma and renal cell carcinoma and has been a central figure in the transition from cytokine monotherapy to checkpoint blockade. He led pivotal nivolumab and nivolumab plus ipilimumab trials in melanoma. His career spans the full arc of modern cancer immunotherapy.
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🧪Research Fields 研究领域
high dose IL-2
checkpoint inhibitor melanoma
IL-2 renal cell carcinoma
nivolumab trials
cytokine immunotherapy history
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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