Steven Joffe
史蒂文·乔夫
MD, MPH
Chief, Division of Medical Ethics; Emanuel and Robert Hart Professor医学伦理学部主任；哈特讲席教授
👥Biography 个人简介
Steven Joffe is an internationally recognized expert in pediatric oncology ethics and clinical trial ethics. His empirical and normative research on informed consent, pediatric assent, and the ethics of early-phase trials has profoundly influenced IRB standards and pediatric oncology trial conduct.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Pediatric Oncology Informed Consent
Conducted definitive empirical studies on parental understanding and decision-making in pediatric cancer trials, revealing systemic gaps and driving consent reform.
Ethics of Phase I Pediatric Oncology Trials
Developed ethical frameworks for enrolling children in first-in-human oncology studies, balancing potential benefit with risk and autonomy considerations.
Therapeutic Misconception in Cancer Research
Produced landmark research on therapeutic misconception in oncology trial participants, advancing theoretical understanding and practical reform of consent processes.
Representative Works 代表性著作
Consent and Assent in Pediatric Oncology Research
Journal of Clinical Oncology (2003)
Seminal study examining parent and child understanding of consent in pediatric cancer trials, identifying critical gaps.
Therapeutic Misconception in Early Phase Gene Transfer Trials
Social Science & Medicine (2001)
Pioneering empirical study demonstrating prevalence and consequences of therapeutic misconception among oncology trial participants.
Toward Ethical Pediatric Oncology Trials: Balancing Benefit, Risk, and Autonomy
Pediatric Blood & Cancer (2008)
Normative framework for the ethical evaluation of risks and potential benefits in pediatric cancer drug trials.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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