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Translational Medicine / 转化医学Bone Tumor, Giant Cell Tumor Denosumab

Steven Gitelis

MD

🏢Rush University Medical Center🌐USA

Professor of Orthopedic Surgery

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👥Biography 个人简介

Steven Gitelis is an orthopedic oncologist who has contributed to research on giant cell tumor of bone (GCT), particularly the use of denosumab to downstage lesions by inhibiting RANK-ligand-driven osteoclastic activity before surgical resection. His work has clarified the role of denosumab in unresectable or recurrent GCT and the risk of recurrence after medical and surgical therapy. He is a founding member of the Musculoskeletal Tumor Society.

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🧪Research Fields 研究领域

giant cell tumor of bone
denosumab GCT
RANK-ligand GCT
curettage GCT recurrence
surgical treatment bone tumors

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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