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Translational Medicine / 转化医学CLL Genetics, 17p Deletion, Venetoclax CLL

Stephan Stilgenbauer

MD

🏢University Hospital Ulm🌐Germany

Professor of Hematology and Oncology

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Key Contributions

👥Biography 个人简介

Stephan Stilgenbauer is a leading CLL geneticist who has contributed fundamentally to understanding the role of chromosomal deletions and mutations, particularly del(17p) and TP53 mutation, in CLL prognosis and treatment selection. His laboratory characterized the genetic landscape of CLL and demonstrated that patients with TP53 dysfunction benefit specifically from BCL-2 inhibition with venetoclax rather than chemotherapy. He has been a co-investigator on venetoclax registration trials and has led major GCLLSG studies. He serves on EMA committees and international CLL guideline panels.

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🧪Research Fields 研究领域

CLL cytogenetics
TP53 mutation
17p deletion
venetoclax
IGHV mutation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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