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Translational Medicine / 转化医学Cancer Splicing Modulators
Peter Smith
PhD
🏢H3 Biomedicine (Eisai)🌐USA
Senior Director of Chemistry, Splicing Modulators
25
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Key Papers
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Key Contributions
👥Biography 个人简介
Peter Smith led medicinal chemistry efforts on splicing modulators including analogs of pladienolide B that target SF3B1 for cancer therapy. His work supported the development of H3B-8800 as an orally bioavailable clinical candidate. He is a specialist in spliceosome-targeted drug chemistry.
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🧪Research Fields 研究领域
medicinal chemistry
SF3B1 ligands
pladienolide analogs
cancer splicing
oral splicing modulators
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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