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Translational Medicine / 转化医学HER2 Discovery, Trastuzumab

Dennis Slamon

MD, PhD

🏢UCLA Jonsson Comprehensive Cancer Center🌐USA

Director, Clinical/Translational Research

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Key Contributions

👥Biography 个人简介

Dennis Slamon led the seminal work that established HER2 as a driver in breast cancer and translated this into the development of trastuzumab, transforming HER2-positive disease. He subsequently contributed to the development of CDK4/6 inhibitors in hormone receptor-positive breast cancer. He remains a leader in breast cancer translational research at UCLA.

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🧪Research Fields 研究领域

HER2
trastuzumab
breast cancer biology
CDK4/6 inhibitors
translational research

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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