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Translational Medicine / 转化医学Milestone 800 Oncology Figures

Dennis Slamon

MD, PhD

🏢University of California, Los Angeles🌐USA

Director, Clinical/Translational Research

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Key Contributions

👥Biography 个人简介

Dennis Slamon discovered that HER2 overexpression drives aggressive breast cancer and developed trastuzumab (Herceptin), transforming HER2-positive breast cancer from the worst to one of the most treatable subtypes. His bench-to-bedside work is one of the greatest success stories in cancer research. The impact of his discovery continues to expand with new HER2-directed agents including T-DXd.

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🧪Research Fields 研究领域

HER2 discovery
Trastuzumab development
Breast cancer
Translational medicine
Oncogene-targeted therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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