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Translational Medicine / 转化医学Comprehensive Genomic Profiling, Biomarkers

Siraj Ali

MD, PhD

🏢Foundation Medicine🌐USA

Chief Scientific Officer

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Key Contributions

👥Biography 个人简介

Dr. Siraj Ali is a pioneering oncologist and scientist who has driven the clinical adoption of comprehensive genomic profiling (CGP) as a standard oncology tool. As CSO at Foundation Medicine, he led development of validated TMB and MSI-H measurements used in FDA approvals of pembrolizumab. His research has defined how CGP-derived biomarkers can guide immunotherapy decisions across cancer types.

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🧪Research Fields 研究领域

comprehensive genomic profiling
MSI-H detection
TMB measurement
tumor immune profiling
pan-cancer biomarkers

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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