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Translational Medicine / 转化医学Mantle Cell Lymphoma, BTK Inhibitors

Simon Rule

MD, FRCP, FRCPath

🏢University of Plymouth / Derriford Hospital🌐UK

Professor of Clinical Haematology

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Key Contributions

👥Biography 个人简介

Simon Rule is a leading international authority on mantle cell lymphoma and pioneered the use of ibrutinib in relapsed/refractory MCL. He led key phase II studies that supported ibrutinib approval in MCL. His work spans MCL biology, novel targeted agents, and treatment sequencing. He serves on multiple international lymphoma guideline committees.

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🧪Research Fields 研究领域

mantle cell lymphoma
ibrutinib
BTK inhibitors
relapsed lymphoma
clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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